Publications

Our former award recipients often notify us of the publication of journal articles and other materials that summarize research that was supported in part by a Foundation grant.

Publications

FY2017 Grant Recipients
Title of the research project Epigenetic and Metabolic Changes on transdifferentiation of white adipocytes
Recipient (Institution) Takeshi Inagaki(Institute for Molecular and Cellular Regulation, Gunma University, professor)
Journal article / other material Endocrine Journal vol.66,No2(February 2019)
Published by The Japan Endocrine Society
Title of the paper Epigenetic regulation of beige adipocyte fate by histone methylation
Journal article / other material Diabetology International(2018) 9:215-223
Title of the paper Histone demethylases regulate adipocyte thermogenesis
Title of the research project Neural circuits that regulate glucose metabolism between hypothalamus and peripheral organs
Recipient (Institution) Kunio Kondoh(National Institute for Physiological Sciences, Assistant Professor )
Journal article / other material Neuroscience Bulletin,20 September 2018
doi:/10.1007/s12264-019-00374-9
Title of the paper Trans-synaptic Neural Circuit-Tracing with Neurotropic Viruses
Title of the research project Heart Cell Molecular Atlas Project to dissect the regulatory mechanisms of circulatory homeostasis
Recipient (Institution) Seitaro Nomura(The University of Tokyo Hospital, Assistant Professor)
Journal article / other material Nature Communications volume 9, Article number: 4435 (2018)
Title of the paper Cardiomyocyte gene programs encoding morphological and functional signatures in cardiac hypertrophy and failure
Journal article / other material Journal of Molecular and Cellular Cardiology,
March 2019Volume 128, Pages 77-89
Title of the paper High-throughput single-molecule RNA imaging analysis reveals heterogeneous responses of cardiomyocytes to hemodynamic overload
Title of the research project Study on the enantioselective total synthesis of dragmacidin E: a natural product with high potential for medicinal chemistry researches
Recipient (Institution) Tetsuhiro Nemoto(Graduate School of Pharmaceutical Sciences, Chiba University, Professor)
Journal article / other material ASIAN JOURNAL OF ORGANIC CHEMISTRY Vol.7,2018,P1730-1742
Title of the paper Synthetic Methods for 3,4‐Fused Tricyclic Indoles via Indole Ring Formation
Title of the research project Development of combination therapy targeting on tumor endothelial cells
Recipient (Institution) Takahisa Murata(The University of Tokyo, Associate Professor)
Journal article / other material THE FASEB JOURNAL,vol33 doi/10.1096/201802153R
Title of the paper Hematopoietic prostaglandin D synthase-derived prostaglandin D2 ameliorates adjuvant-induced joint inflammation in mice
Journal article / other material JCI Insight. 2018;3(23):e120706,doi/10.1172
Title of the paper Inhibition of stromal cell-derived factor-1α/CXCR4 signaling restores the blood-retina barrier in pericyte-deficient mouse retinas
Journal article / other material The journal of pathology ,2019,Vol.248(3),p.280-290
Title of the paper L-PGDS-derived PGD2attenuates acute lung injury by enhancing endothelial barrier formation
Title of the research project Development of anti-metastatic therapy based on the regulation of vascular integrity
Recipient (Institution) Takayuki Shindo(Shinshu University Graduate School of Medicine, Professor)
Journal article / other material Peptides,Volume 110, December 2018, Pages 10-18
doi.10.1016/j.peptides.2018.10.006
Title of the paper RAMP3 deficiency enhances postmenopausal obesity and metabolic disorders
Journal article / other material The American Journal of Pathology,Volume 189, Issue 2, February 2019, Pages 449-466,doi/10.1016/j.ajpath.2018.10.021
Title of the paper Development of a Novel Model of Central Retinal Vascular Occlusion and the Therapeutic Potential of the Adrenomedullin-Receptor Activity-Modifying Protein 2 System
Title of the research project Studies on formation and function of extracellular DNA fibers
Recipient (Institution) Hisato Saitoh(Kumamoto University, Professor)
Journal article / other material SCIENTIFIC REPORTS,(2019)9:8451
doi:10.1038/s41598-019-44817-9
Title of the paper Nanosecond pulsed electric fields induce extracellular release of chromosomal DNA and histone citrullination in neutrophil-differentiated HL-60 cells
Title of the research project 5-HT2A receptor agonists in treatment to psychiatric disorders
Recipient (Institution) Daisuke Ibi(Meijo University, Assistant Professor)
Journal article / other material Neuropsychopharmacology,44, pages443-454(2019)
doi:10.1038/s41386-018-0143-4
Title of the paper Chronic clozapine treatment restrains via HDAC2 the performance of mGlu2 receptor agonism in a rodent model of antipsychotic activity
Title of the research project Novel treatment strategy targeting CCR1-positive myeloid cells in colorectal cancer
Recipient (Institution) Kenji Kawada(Kyoto University, Lecturer)
Journal article / other material Clinical Cancer Research May 1 2019 25 (9) 2887-2899;
DOI:10.1158/1078-0432.CCR-18-3684
Title of the paper Loss of SMAD4 Promotes Colorectal Cancer Progression by Recruiting Tumor-Associated Neutrophils via the CXCL1/8-CXCR2 Axis
Title of the research project Design principle for specific chemical probes toward 3D neuropathology
Recipient (Institution) Kazuki Tainaka(Brain Research Institute, Niigata University, Specially Appointed Professor)
Journal article / other material Cell Reports 24,2196-2210,doi/10.1016/j.celrep.2018.07.056
Title of the paper Chemical Landscape for Tissue Clearing Based on Hydrophilic Reagents
FY2016 Grant Recipients
Title of the research project Identification of novel neural processing mechanism by using single transcriptome analysis
Recipient (Institution) Akane Ohta(Konan University, Researcher)
Journal article / other material Cryobiology and Cryotechnology 64.2_53 (2019)
doi./10.20585/
Title of the paper Molecular and Cellular Network Systems Underlying Cold Tolerance of Caenorhabditis elegans
Title of the research project Genome-wide analysis of transcriptional and translational regulation by RNA binding protein PSF in prostate cancer
Recipient (Institution) Kenichi Takayama Department of Functional Biogerontology, Tokyo Metropolitan Inst, Researcher)
Journal article / other material Oncogene 37, 2165-2180, (2018)
https://doi.org/10.1038/s41388-017-0095-x
Title of the paper TRIM25 enhances cell growth and cell survival by modulating p53 signals via interaction with G3BP2 in prostate cancer
Title of the research project Study on the Mechanism of Sex Determination in Germline Stem Cells
Recipient (Institution) Minoru Tanaka(Nagoya University, Professor)
Journal article / other material PLOS Genetics 14, (2018)
https://doi.org/10.1371/journal.pgen.1007259
Title of the paper Germ cells in the teleost fish medaka have an inherent feminizing effect
Title of the research project Elucidation of the onset mechanism of myeloproliferative neoplasm through the erythropoietin receptor
Recipient (Institution) Megumi Tago(Keio University, Associate Professor)
Journal article / other material European Journal of Pharmacology 825, 1-9, (2018)
https://doi.org/10.1016/j.ejphar.2018.02.012
Title of the paper A major component of vitamin E, α-tocopherol inhibits the anti-tumor activity of crizotinib against cells transformed by EML4-ALK
Title of the research project Selective information routing in hippocampal network
Recipient (Institution) Mizuseki Kenji(Osaka City University Graduate School of Medicine, Professor)
Journal article / other material Neuroscience Research 118, 30-47, (2017)
http://dx.doi.org/10.1016/j-neures.2017.04.018
Title of the paper Hippocampal information proccessing across sleep/wake cycles
FY2015 Grant Recipients
Title of the research project Control of host immune responses through innate pattern-recognition receptors that recognize Mycobacterium tuberculosis virulence lipids
Recipient (Institution) Hiromitsu Hara, Kagoshima University Graduate School of Medical and Dental Sciences, Professor
Journal article / other material Nature Communications 6:5555
doi:10.1038/ncomms6555
Title of the paper Clustering of CARMA1 through SH3-GUK domain interactions is required for its activation of NF-κB signaling
Title of the research project Molecular mechanism of plant cell growth via NIMA-related kinases
Recipient (Institution) Hiroyasu Motose, Okayama University, Department of Biological Science, Graduate School of Natural Science & Technology, Associate Professor
Journal article / other material Development (2018) 145, dev154617
doi:10.1242/dev.154617
Title of the paper An evolutionarily conserved NIMA-related kinase directs rhizoid tip growth in the basal land plant Merchantia polymorpha
Journal article / other material Scientific Report 7, 7826
doi:10.1038/s41598-017-08453-5
Title of the paper Directional cell expansion requires NIMA-related kinase 6 (NEK6)-mediated cortical microtubule destabilization
Title of the research project Analysis of a signal through ER required for the induction of axon regeneration
Recipient (Institution) Naoki Hisamoto, Nagoya university Graduate school of Science, Associate Professor
Journal article / other material PLoS 12(12):e1006475
doi:10.1371/journal.pgen.1006475
Title of the paper The C. elegans Discoidin Domain Receptor DDR-2 Modulates the Met-like RTK-JNK Singnaling Pathway in Axon Regeneration
Title of the research project Development of molecular delivery system using cell membrane penetrating DNA nanostructures
Recipient (Institution) Masayuki Endo, Kyoto University, Institute for Integrated Cell-Material Sciences (WPI-iCeMS),
Journal article / other material Chem. Eur. J 23, 3979-3985 (2017)
doi:10.1002/chem.201605616
Title of the paper A photoregulated DNA-Based Rotary System and Direct Observation of Its Rotational Movement
Title of the research project Functional significance of Chandelier cell in cortical microcircuit
Recipient (Institution) Yoshiyuki Kubota, National Institute for Physiological Sciences, Associate professor
Journal article / other material Front Neural Circuits 10, 27 (2016)
doi:10.3389/fncir.2016.00027
Title of the paper The Diversity of Cortical Inhibitory Synapses
Journal article / other material Nat Commun 9, 437 (2018)
doi:10.1038/s41467-017-02768-7
Title of the paper A catructurerbon nanotube tape for serial-section electron microscopy of brain ultra
Title of the research project Cortical synaptic plasticity for coexistence of chronic pain and anxiety neurosis
Recipient (Institution) Kohei Koga, Hirosaki University Department of Neurophysiology, Assistant
Journal article / other material J. Neurochem. 141 486-498 (2017)
Title of the paper Neuronal and microglial mechanisms for neuropathic pain in the spinal dorsal horn and anterior cingulate cortex
Title of the research project Functional analysis of a novel silencing mechanism in higher plants
Recipient (Institution) Kei-ichiro Mishiba, Graduate School of Life and Environmental Science, Osaka Prefecture University, Associate
Journal article / other material Science Direct 1860, 861-869 (2017)
https:doi.org/10.1016/j.bbagrm.2017.06.001
Title of the paper Biochimica et Biophysica Acta (BBA) Gene Regulatory Mechanisms
Title of the research project The origin of animal multicellular system an approach from genome editing of unicellular holozoans
Recipient (Institution) Hiroshi Suga, Prefectural University of Hiroshima, Faculty of Life and Environmental Sciences, Associate Professor
Journal article / other material eLife 2017 6:e26036
doi:10.7554/eLife.26036
Title of the paper Dynamics of genomic innovation in the unicellular ancestry of animals
Title of the research project Regulating microtubule arrays for neuronal dendrite growth and for neuronal regeneration
Recipient (Institution) Adrian Moore(RIKEN Center for Brain Science)
Journal article / other material Plant Physiology,182,1979-1990(2020)
Title of the paper Atypical Myosin Tunes Dendrite Arbor Subdivision
FY2014 Grant Recipients
Title of the research project Effect of dendritic cell based vaccine against highly virulent cryptococcal infection
Recipient (Institution) Yuki Kinjo (National Institute of Infectious Diseases, Department of Chemotherapy and Mycoses, LaboratoryHead)
Journal article / other material Frontiers in Cellular and infection Microbiology 5:101 Doi: 10.3389/fcimb.2015.00101 (2016)
Title of the paper Evasion of innate immune responses by the highly virulent Cryptococcus gatti by altering capsule glucuronoxylomannan structure
Journal article / other material J Infect Chemother., 21, 831-6 (2015)
Title of the paper Interferon-γ promotes phagocytosis of Cryptococcus neoformans but not Cryptococcus gatti by murine macrophages
Journal article / other material Vaccine Design: methods and Protocols: volume 1: vaccines for Human Diseases, method in Molecular Biology, vol 1.1403, DOI 10.1007/978-1-49393387-7_30
Title of the paper Dendric cell-based vaccine against fungal infection
Title of the research project Nano scale analysis of lipid molecules of biomembrane topology
Recipient (Institution) Akikazu Fujita (Kagoshima University, Joint Faculty of Veterinary Medicine, Professor)
Journal article / other material Biochimica Biophysica Acta, 1858, 1298-305 (2016)
Title of the paper Nanoscale analysis reveals agonist-sensitive and heterogeneous pools of phosphatidylinositol 4-phosphate in the plasma membrane
Title of the research project Positive feed-forward loop of mTOR complex links cellular metabolism to targeted therapy resistance
Recipient (Institution) Kenta Masui (Laboratory of Neuropathology, Tokyo Metropolitan Institute of Medical Science, Chief Researcher)
Journal article / other material Brain pathology, 25, 755-9 (2015)
Title of the paper mTORC2 and metabolic reprogramming in GBM: at the interface of genetics and environment
Journal article / other material www.pnas.org/cgi/doi/10.1073/pnas.1511759112
Title of the paper Glucose-dependent acetylation of rictor promotes targeted cancer therapy resistance
Title of the research project Analysis of molecular mechanisms for cell fate determination of retinal interneurons
Recipient (Institution) Rikako Sanuki (Osaka University, Institute for Protein Research, Assistant Professor)
Journal article / other material J Neuroscience, 35, 8004-20 (2015)
Title of the paper Prdm13 regulates subtype specification of retinal amacrine interneurons and modulates visual sensitivity
Journal article / other material Molecular and Cellular Biology, 35, 2583-96 (2015)
Title of the paper Rax homoprotein regulates photoreceptor cell maturation and survival in association with Crx in the postnatal mouse retina
Title of the research project Drug discovery for neuropathic pain from processed aconite root
Recipient (Institution) Toshiaki Makino (Nagoya City University,Graduate School of Pharmaceutical Sciences, Professor)
Journal article / other material Journal of Ethnopharmacoloy, 186, 44-52 (2016)
Title of the paper Processed aconite root and its active ingredient neoline may alleviate oxaliplatin-induced peripheral neuropathic pain
Title of the research project Development of a comprehensive synthetic strategy and study of biological activity of yuzurimine alkaloids
Recipient (Institution) Ichiro Hayakawa (Graduate School of Natural Science and Technology, Okayama University, Associate Professor)
Journal article / other material Chem. Commun., 51, 11568-71 (2015)
Title of the paper Construction of the [6-7-5-5] tetracyclic core of all the carbocyclic frameworks of yuzurimine-type alkaloids
Journal article / other material Org. Biomol. Chem., 13, 9969-76 (2015)
Title of the paper Synthesis and structure-activity relationships for cytotoxicity and apoptosis-inducing activity of (+)-halichonine B
Title of the research project Development of novel therapy for peripheral artery disease using ApoA-I mimetic peptide
Recipient (Institution) Satoshi Imaizumi (Fukuoka University School of Medicine, Assistant Professor)
Journal article / other material International Journal of Cardiology, 207, 317-25 (2016)
Title of the paper The ApoA-I mimetic peptide FAMP promotes recovery from hindlimb ischemia through a nitric oxide (NO)-related pathway
Title of the research project Regulation mechanisms of retroelements by RNA virus
Recipient (Institution) Tomoyuki Honda (Institute for Virus Research, Kyoto University, Assistant Professor)
Journal article / other material Cell reports, 12, 1948-54 (2015)
Title of the paper Transcription profiling demonstrates epigenetic control of non-retroviral RNA virus-derived elements in the human genome
Journal article / other material Frontiers in Chemostry, 4, doi:10.3389/fchem.2016.00021
Title of the paper Links between human LINE-1 retrotransposons and hepatitis virus-related hepatocellular carcinoma
Journal article / other material Mobile Genetic Elements, 6, Doi: 10.1080/2159256X.2016. 1165785
Title of the paper Endogenous non-retroviral RNA virus elements evidence a novel type of antiviral immunity
Journal article / other material Nature Scientific reports, 6, 26154, Doi: 10.1038/srep26154
Title of the paper Long-term expression of miRNA for RNA interface using a novel vector system based on a negative-strand RNA virus
Title of the research project Research on the regulation of chronic inflammatory disease by plasmacytoid dendritic cells
Recipient (Institution) Hideaki Takagi (Faculty of Medicine, University of Miyazaki, Assistant Professor)
Journal article / other material Nature Communications, 7, 11273,Doi:10.1038/nocommons11273
Title of the paper Plasmacytoid dendritic cells orchestrate TLR7-mediated innate and adaptive immunity for the initiation of autoimmune inflammation
Title of the research project Genome-wide screening of endocytosis of GPCR
Recipient (Institution) Junko Toshima (Faculty of Science And Engineering, Waseda University, Associate Professor)
Journal article / other material Biochemical and Biophysical Research Communications, xxx, 1-7 (2016).doi.org/10.1016/j.bbrc.2016.05.099
Title of the paper Lipid droplet proteins, Lds1p, Lds2p and Rrt8p, are implicated in membrane protein transport associated with ergosterol
Journal article / other material Journal of Cell Science, 129, 367-79 (2016), doi:10.1242/jcs.176651
Title of the paper Srv2/CAP is required for polarized actin cable assembly and patch internalization during clathrin-mediated endocytosis
FY2013 Grant Recipients
Title of the research project CARTS-mediated protein transport from the Golgi complex to the cell surface
Recipient (Institution) Yuichi Wakana(Tokyo University of Pharmacy and Life Sciences, School of Life Sciences)
Journal article / other material Molecular Biology of the Cell, 26, 4686-4699, (2015)
Title of the paper CARTS biogenesis requires VAP-lipid transfer protein complexes functioning at the endoplasmic reticulum-Golgi interface
Title of the research project Discovery of New Drug Candidates Based on Development of Site-selective Direct Functionalization of Pyridones
Recipient (Institution) Koji Hirano(Department of Applied Chemistry, Graduate School of Engineering, Osaka University)
Journal article / other material Angewandte Communications: 53, 10784-10788 (2014)
Title of the paper Copper-Mediated C6-Selective Dehydrogenative Heteroarylation of 2-Pyridones with 1,3-Azoles
Title of the research project Research on Asymmetric Membrane Elongation Critical for Symmetric Cell Division
Recipient (Institution) Tomomi Kiyomitsu (Nagoya University, Graduate School of Science, Assistant Professor)
Journal article / other material Trends in Cell Biology, May Vol.25, No.5 286-295 (2015)
Title of the paper Mechanisms of daughter cell-size control during cell division
Title of the research project ”Memory priming” that determines the start of the critical period for learning
Recipient (Institution) Koichi Homma (Teikyo University, Faculty of Pharmaceutical Sciences, Professor)
Journal article / other material Communicative & Integrative Biology: Volume7 Issue5 1-4 October 1 , (2014)
Title of the paper Expression of the voltage-sensing phosphatase gene in the chick embryonic tissues and in the adult cerebellum
Title of the research project Dissecting the mechanism of cellular senescence that regulates tumor microenvironment
Recipient (Institution) Shizue Ohsawa (Kyoto University, Graduate School of Biostudies, Associate Professor)
Journal article / other material Developmental Biology 395, 19-28(2014)
Title of the paper Loss of Rab5 drives non-autonomous cell proliferation through TNF and Ras signaling in Drosophila
Journal article / other material Nature Communications DOI:10.1038/ncomms6264 (2014)
Title of the paper Mitochondrial defects trigger proliferation of neighbouring cells via a senescence-associated secretory phenotype in Drosophila
Title of the research project Development of novel treatment strategies targeting the R-spondin-LGR5 axis of brain tumor stem cells
Recipient (Institution) Ryo Nasu (Kyoto Prefectural University of Medicine, Assistant Professor)
Journal article / other material BBRC(Biochemical and Biophysical Research Communications), 459, 411-415(2015)
Title of the paper Thr160 of Axin1 is critical for the formation and function of the β-catenin destruction complex
Title of the research project Elucidating how the auditory information is integrated by morphological techniques
Recipient (Institution) Tetsufumi Ito (University of Fukui, Faculty of Medical Sciences, Assistant Professor)
Journal article / other material The Journal of Comparative Neurology 00:00-00, (2015)
Title of the paper Convergence of Lemniscal and Local Excitatory Inputs on Large GABAergic Tectothalamic Neurons
Journal article / other material Brain Research doi.org/10.1016 (2014)
Title of the paper Determining auditory-evoked activities from multiple cells in layer 1 of the dorsal cortex of the inferior colliculus of mice by in vivo calcium imaging
Title of the research project Membrane type-1 matrix metalloproteinase in multiple myeloma: a novel modulator of the microenvironment
Recipient (Institution) Beate Heissig (The University of Tokyo, The Institute of Medical Science, Associate Professor)
Journal article / other material Leukemia 29,145-156 (2015)
Title of the paper Inhibition of plasmin attenuates murine acute graft-versus-host disease mortality by suppressing the matrix metalloproteinase-9-dependent inflammatory cytokine storm and effector cell trafficking
Title of the research project Research on the role of the novel adipocytokine in heart disease
Recipient (Institution) Noriyuki Ouchi (Nagoya University, Graduate School of Medicine, Professor)
Journal article / other material The FASEB Journal Vol.29 January 141-151 (2015)
Title of the paper Adipose-derived protein omentin prevents neointimal formation after arterial injury
Journal article / other material Circ Heart Fail DOI:10.1161/114.001647(2015)
Title of the paper Neuron-Derived Neurotrophic Factor Ameliorates Adverse Cardiac Remodeling After Experimental Myocardial Infarction
Title of the research project The apoptosis-inducing mechanism of biselyngbyaside, a marine macrolide
Recipient (Institution) Kiyotake Suenaga (Keio University, Faculty of Science and Technology, Associate Professor)
Journal article / other material Organic Letters, 17, 652-655 (2015)
Title of the paper Jahanyne, an Apoptosis-Inducing Lipopeptide from the Marine Cyanobacterium Lyngbya sp.
Journal article / other material Journal of Natural Products78, 901-908 (2015)
Title of the paper Mebamamides A and B, Cyclic Lipopeptides Isolated from the Green Alga Derbesia marina
Title of the research project Functional analysis of a novel suppressive factor at fertilization
Recipient (Institution) Naofumi Miwa (Toho University, School of Medicine, Associate Professor)
Journal article / other material Molecules 20, 9468-9486 (2015)
Title of the paper Protein-Carbohydrate Interaction between Sperm and the Egg-Coating Envelope and Its Regulation by Dicalcin, a Xenopus laevis Zona Pellucida Protein-Associated Protein
Title of the research project Elucidation of the novel signal network that regulates trafficking of secretory lysosomes
Recipient (Institution) Yoshinori Fukui (Kyushu University, Medical Institute of Bioregulation, Professor)
Journal article / other material The Journal of Experimental Medici: Vol.211 No.7 1407-14019 (2014)
Title of the paper DOCK5 functions as a key signaling adaptor that links FcƐRI signals to microtubule dynamics during mast cell degranulation
Title of the research project The Identification of Exosomal Micro RNA Specific for the Recurrence of Hepatocellular Carcinoma
Recipient (Institution) Keishi Sugimachi (Kyushu University Beppu Hospital, Associate Professor)
Journal article / other material British Journal of Cancer: doi: 10.1038/bjc 2014.621 (2014)
Title of the paper Identification of a bona fide microRNA biomarker in serum exosomes that predicts hepatocellular carcinoma recurrence after liver transplantation
Title of the research project Development of a novel catalytic asymmetric method for the incorporation of a biologically significant trifluoromethyl group
Recipient (Institution) Yoshitaka Hamashima (University of Shizuoka, School of Pharmaceutical Sciences, Professor)
Journal article / other material Chemistry European Journal doi:10.1002/chem.201403447 20, 12061-12065 (2014)
Title of the paper Dual Catalysis wit Copper and Rhenium for Trifluoromethylation of Propargylic Alcohols: Efficient Synthesis of α-Trifluoromethylated Enones
Title of the research project Spatiotemporal analysis of oncogenic signaling by Kit tyrosine kinase ~Mechanism of autonomous proliferation in mastocytosis and gastrointestinal stromal tumor (GIST)~
Recipient (Institution) Yuuki Obata (Tokyo University of Science, Research Institute for Biomedical Sciences, Assistant Professor)
Journal article / other material Nature Communications Doi: 10.1038/ncomms6715
Title of the paper Oncogenic Kit signals on endolysosomes and endoplasmic reticulum are essential for neoplastic mast cell proliferation
FY2012 Grant Recipients
Title of the research project Molecular mechanism of temperature response through secretory signaling
Recipient (Institution) Atsushi Kuhara (Faculty of Science and Engineering, Konan University)
Journal article / other material Neurosci Res, 76, 119-24 (2013)
Title of the paper Molecular mechanism for trimetric G protein-coupled thermosensation and synaptic regulation in the temperature repsonse circuit of Caenorhabditis elegans
Title of the research project Elucidation of the mechanisms by which impaired clearance of apoptotic cells results in severe inflammation
Recipient (Institution) Hiroyasu Nakano (Graduate School of Medicine, Juntendo University)
Journal article / other material Biochem Biophys Res Commun, 436, 212-6 (2013)
Title of the paper Critical contribution of oxidative stress to TNF α-induced necrosis downstream of RIPK1 activation
Title of the research project Comprehensive proteomicanalysis of molecules that are targeted for cancer prognosis or therapy
Recipient (Institution) Kiyotsugu Yoshida (School of Medicine, Jikei University)
Journal article / other material Proc Natl Acad Sci USA , 111, 717-22 (2014)
Title of the paper Induction of amphyregulin by p53 promotes apoptosis via control of microRNA biogenesis in response to DNA damage
Journal article / other material Cancer Lett, 339, 214-25 (2013)
Title of the paper DYRK2 controls the epithelial-mesenchymal transition in breast cancer by degrading Snail
Title of the research project Explorative study on lysine demethylase inhibitors by rational drug design
Recipient (Institution) Takayoshi Suzuki (Department of Chemistry, Kyoto Prefectural University of Medicine)
Journal article / other material J Med Chem, 56, 7222-31 (2013)
Title of the paper Identification of the KDM2/7 histone lysine demethylase subfamily inhibitor and its antiproliferative activity
Journal article / other material Angew Chem Int Ed Engl, 52, 8620-4 (2013)
Title of the paper Lysine-specific demethylase 1-selective inactivators: protein-targeted drug delivery mechanism
Journal article / other material Comput Struct Biotechnol J, 9, e201402002 (2014)
Title of the paper Synthesis, LSD1 inhibitory activity, and LSD1 binding model of optically pure lysine-PCPA conjugates
Title of the research project Synthesis of anticancer anthracycline antibiotics having aza-spiro structure
Recipient (Institution) Mitsuru Kitamura (Graduate School of Engineering, Kyushu Institute of Technology)
Journal article / other material Tetrahedron Lett, 55, 1653-6 (2014)
Title of the paper Synthetic study of kosinostatin aglycone: synthesis of BCDE rings using alkoxycarbonylmethylation of diazonaphtoquinone
Title of the research project Identification of cytidine deaminase activity for elucidating the molecular mechanism of plant organelle RNA editing
Recipient (Institution) Mamoru Sugita (Center for Gene Research, Nagoya University)
Journal article / other material Plant Cell Physiol, 54, 1907-16 (2013)
Title of the paper Two DYW subclass PPR proteins are involved in RNA editing of ccmFc and atp9 transcripts in the Moss Physcomitrella patens: first completes set of PPR editing factors in plant mitochondria
Title of the research project RAC1 inhibitor is an anti-tumor metastasis drug
Recipient (Institution) Satoru Yokoyama (Institute of Natural Medicine, Toyama University)
Journal article / other material Cancer Sci, 105, 788-94 (2014)
Title of the paper RAC1 inhibition as a therapeutic target for gefitinib-resistant non-small-cell lung cancer
Title of the research project Molecular mechanism of Derlin family-mediated novel endoplasmic reticulum quality control system
Recipient (Institution) Hideki Nishitoh (Department of Medical Sciences, University of Miyazaki)
Journal article / other material Genes(Basel), 4, 306-33 (2013)
Title of the paper Signaling pathways from the endoplasmic reticulum and their roles in disease
Title of the research project Epigenetic regulation by nuclear pore complex in cancer progression.
Recipient (Institution) Richard Wong (Institute of Science and Engineering, Kanazawa University)
Journal article / other material Cell Cycle, 10, 1456-67 (2011)
Title of the paper RNA export factor RAE1 contributes to NUP98-HOXA9-mediated leukemogenesis
Title of the research project Elucidation of molecular functions of Imp3 in osteosarcoma progression, and development of novel anti-Imp3 targeted therapeutic approach
Recipient (Institution) Takatsune Shimizu (Faculty of Pharmaceutical Sciences, Hoshi University)
Journal article / other material Cancer Res, 74, 6531-41 (2014)
Title of the paper IGF2 preserves osteosarcoma cell survival by creating an autophagic state of dormancy that protects cells against chemotherapeutic stress
Title of the research project Synthetic Studies on the virulent cell wall lipid of Mycobacterium tuberculosis
Recipient (Institution) Seijiro Hosokawa (Faculty of Science and Engineering, Waseda University)
Journal article / other material Org Lett, 16, 4106-9 (2014)
Title of the paper Stereoselective acylation of the E,E-vinylketene Silyl N,O-acetal and its application to the synthesis of khafrefungin
Title of the research project Development of an orange-colored bimolecular fluorescence complementation (BiFC) assay
Recipient (Institution) Yutaka Kodama (Center for Bioscience Research and Education, Utsunomiya University)
Journal article / other material The 12th Japan Prize in Agrecultural Sciences, Achievement Award for Young Scientists (The Foundation of Agrecultural Sciences of Japan)
Title of the paper Visualization of protein-protein interactions in living cells
Title of the research project Regulation of plasma membrane receptor-like kinase functions by endoplasmic reticulum quality control in plant cells
Recipient (Institution) Shuh-ichi Nishikawa(Faculty of Science, Niigata University)
Journal article / other material Plant Physiology,182,1979-1990(2020)
Title of the paper ERdj3B-Mediated Quality Control Maintains Anther
Development at High Temperatures
FY2011 Grant Recipients
Title of the research project Molecular mechanism of self-renewal and proliferation of a hematopoietic cell due to HMGA2 expression
Recipient (Institution) Kazuhiko Ikeda (Department of Cardiology and Hematology, Fukushima Medical University)
Journal article / other material Clin Lymphoma Myeloma Leuk, 14, e69-72 (2014)
Title of the paper Somatic 15q break after long-term stable disease in acute myeloid leukemia
Journal article / other material Br J Haematol, 168, 388-49 (2015)
Title of the paper Dysregulation of the MIRLET7/HMGA2 axis with methylation of the CDKN2A promoter in myeloproliferative neoplasms
Title of the research project The Role of transcription factor Iκβ-ζ in immunity homeostasis
Recipient (Institution) Takashi Maruyama (Graduate School of Life Sciences, Tohoku University)
Journal article / other material PLoS One, 9, e110838 (2014)
Title of the paper The nuclear IκB family protein IκBNS influences the susceptibility to experimental autoimmune encephalomyelitis in a murine model
FY2007 Grant Recipients
Title of the research project Analysis of new zebrafish mutants that show the defects in gut epithelium formation.
Recipient (Institution) Yutaka Kikuchi (Graduate School of Science, Hiroshima University)
Journal article / other material PLoS One, 7, e33675 (2012)
Title of the paper DEAD-box protein Ddx46 is required for the development of the digestive organs and brain in zebrafish