Publications

Our former award recipients often notify us of the publication of journal articles and other materials that summarize research that was supported in part by a Foundation grant.

Publications

FY2019 Grant Recipients
Title of the research project Evolution of membrane morphogenesis in Asgard archaea
Recipient (Institution) Yosuke Senju(Research Institute for Interdisciplinary Science (RIIS),Okayama University)
Journal article / other material Springer Science+Business Media, LLC, part of Springer Nature 2021
doi.org/10.1007/978-1-0716-1142-5_14
Title of the paper Liposome Co-sedimentation and Co-flotation Assays to Study Lipid-Protein Interactions
Title of the research project Cell senescence effects on transcriptional regulation and differentiation in beige preadipocytes
Recipient (Institution) Kenji Ikeda(Department of Molecular Endocrinology and Metabolism,Tokyo Medical and Dental University)
Journal article / other material Front Endocrinol (Lausanne). 2020 Jul 28; 11: 498
doi: 10.3389/fendo.2020.00498
Title of the paper UCP1 Dependent and Independent thermogenesis in Brown and Beige Adipocytes
Title of the research project Molecular mechanism underlying development of memory-like Group 2 innate lymphoid cells
Recipient (Institution) Takashi Ebihara(Department of Medical Biology,Akita University Graduate School of Medicine)
Journal article / other material Cells 2020, 9, 1193;
doi:10.3390/cells9051193
Title of the paper Dichotomous Regulation of Acquired Immunity by Innate Lymphoid Cells
Journal article / other material Allergology International 70 (2) 2021, 174-180
doi.org/10.1016/j.alit.2020.11.007
Title of the paper Trained innate lymphoid cells in allergic diseases
Title of the research project In vivo Imaging of Brain in CNS Lupus Defines Unique Roles for Chemoattractants
Recipient (Institution) Yoshishige Miyabe(Institute for Advanced Medical Sciences,Nippon Medical School)
Journal article / other material JMA J. 2020;3(3):
DOI: 10.31662/jmaj.2020-0019
Title of the paper Targeting the Chemokine System in Rheumatoid Arthritis and Vasculitis
Title of the research project Mechanisms involved in regulation of osteoclast formation by glucan recognition via immune receptors
Recipient (Institution) Wataru Ariyoshi(Division of Infections and Molecular Biology,Kyushu Dental University)
Title of the paper Molecules 2021, 26, 1982
doi.org/10.3390/molecules26071982
Journal article / other material Biological Effects of β-Glucans on Osteoclastogenesis
Title of the research project Elucidation of the promotion mechanism in plant shoot regeneration by environmental stimuli
Recipient (Institution) Sachihiro Matsunaga(Matsunaga Laboratory, Department of Applied Biological Science, Faculty of Science and Technology,Tokyo University of Science)
Journal article / other material NATURE COMMUNICATIONS (2020) 11:5914
doi.org/10.1038/s41467-020-19621-z
Title of the paper Subnuclear gene positioning through lamina association affects copper tolerance
Journal article / other material Communications biology 14, May 2021
doi.org/10.1038/s42003-021-02106-0
Title of the paper A live imaging system to analyze spatiotemporal dynamics of RNA polymerase II modification in Arabidopsis thaliana
Title of the research project Molecular and neural mechanism associated with social behavior
Recipient (Institution) Teiichi Furuichi(Department of Biological Science, Faculty of Science and Technology,Tokyo University of science)
Journal article / other material Front. Cell. Neurosci. 2020, 14: 595607.
doi: 10.3389/fncel.2020.595607.
Title of the paper Comprehensive Profiling of Gene Expression in the Cerebral Cortex and Striatum of BTBRTF/ArtRbrc Mice Compared to C57BL/6J Mice.
Journal article / other material Cell Tissue Res. 2020, 382(1):125-134.
doi: 10.1007/s00441-020-03274-x.
Title of the paper Journey of brain-derived neurotrophic factor: from intracellular trafficking to secretion
Journal article / other material The Journal of Neuroscience, May 19, 2021
doi.org/10.1523/JNEUROSCI.3240-20.2021
Title of the paper CAPS2 Deficiency Impairs the Release of the Social Peptide Oxytocin, as Well as Oxytocin-Associated Social Behavior
Title of the research project Identification of molecular mechanism underlying drug resistance by tumor-stroma derived exosome
Recipient (Institution) Takatsugu Ishimoto(Division of Translational Research and Advanced Treatment Against Gastrointestinal Cancer,Kumamoto University Hospital)
Journal article / other material Cancer Res. 2020; 80(16): 3222-3235
doi: 10.1158/0008-5472.CAN-19-3803
Title of the paper Extracellular Vesicles from Cancer-Associated Fibroblasts Containing Annexin A6 Induces FAK-YAP Activation by Stabilizing b1 Integrin, Enhancing Drug Resistance
Title of the research project The ultrastabilization mechanism of amyloid revealed by a protein engineering technique
Recipient (Institution) Koki Makabe(School of science and engineering, Makabe lab.,Yamagata university)
Journal article / other material 2021 Wiley Periodicals LLC, 8 February 2021
DOI: 10.1002/prot.26063
Title of the paper Structural analysis of the β-sheet edge of peptide self-assembly using a model protein
Title of the research project Identification of the lipid species which regulate epidermis differentiation in Arabidopsis
Recipient (Institution) Mitsutomo Abe(Graduate School of Arts and Sciences,The University of Tokyo)
Journal article / other material The Company of Biologists, Development (2021) 148, dev194969. doi:10.1242ldev.194969
Title of the paper Ceramides mediate positional signals in Arabidopsis thaliana protoderm differentiation
FY2018 Grant Recipients
Title of the research project Fundamental study for GATA3 transcriptional complex and new insight into functional role of type2 innate lymphoid cells to control life-style related disease
Recipient (Institution) Tanaka Tomoaki(Chiba University, Graduate School Medicine)
Journal article / other material eNeurologicalSci. 19:100239, 2020
10.1016/j.ensci.2020.100239
Title of the paper Monoamine oxidase B rs1799836 G allele polymorphism is a risk factor for early development of levodopa-induced dyskinesia in Parkinson's disease.
Journal article / other material Endcrine Journal. 67(8):841-852 2020.
https://doi.org/10.1507/endocrj.EJ19-0617
Title of the paper A multicenter, phase 2 study to evaluate the efficacy and safety of osilodrostat, a new 11β-hydroxylase inhibitor, in Japanese patients with endogenous Cushing’s syndrome other than Cushing’s disease.
Journal article / other material J Clin Endocrinol Metab., Epub., 105(2): dgz073, 202
DOI:10.1210/clinem/dgz073
Title of the paper A case of Hashimoto’s thyroiditis with multiple drug resistance and high expression of efflux transporters.
Title of the research project Importance of tissue-resident memory T cells in mucosal tissue
Recipient (Institution) Iijima Norifumi(National Institutes of Biomedical Innovation, Health and Nutriti)
Journal article / other material Curr Top Microbiol Immunol. 2020, 426, 83
10.1007/82_2020_213.
Title of the paper Memory Lymphocyte Clusters in Genital Immunity: Role of Tissue-Resident Memory T Cells (TRM).
Title of the research project Analysis of cell lineage and transcriptional regulation during ventricular development of heart
Recipient (Institution) Watanabe Yusuke(Molecular Phys lab, National Cerebral and Cardiovascular Center)
Journal article / other material Dev Biol. 2020;461(2):124-131.
doi: 10.1016/j.ydbio.2020.02.001.
Title of the paper Expression of Hey2 transcription factor in the early embryonic ventricles is controlled through a distal enhancer by Tbx20 and Gata transcription factors
Journal article / other material J Biol Chem. 2020;295(51):17632-17645.
doi: 10.1074/jbc.RA120.015003.
Title of the paper Importance of endothelial Hey1 expression for thoracic great vessel development and its distal enhancer for Notch-dependent endothelial transcription
Journal article / other material Dev Growth Differ. 2021;63(1):82-92.
doi: 10.1111/dgd.12707.
Title of the paper A role of Hey2 transcription factor for right ventricle development through regulation of Tbx2-Mycn pathway during cardiac morphogenesis
Title of the research project Pathophysiologic role of a novel microenvironment that prolongs tissue damage in acute kidney injury
Recipient (Institution) Suganami Takayoshi(Dept. of Molecular Medicine and Metabolism, Nagoya University)
Journal article / other material J Exp Med. 2020; 217: e20192230
doi: 10.1084/jem.20192230.
Title of the paper C-type lectin Mincle mediates cell death-triggered inflammation in acute kidney injury.
Title of the research project Development of new base editor systems
Recipient (Institution) Yachie Nozomu(RCAST, The University of Tokyo)
Journal article / other material Nature Biotechnology 38, 865-869 (2020)
doi.org/10.1038/s41587-020-0509-0
Title of the paper Base editors for simultaneous introduction of C-to-T and A-to-G mutations.
Title of the research project Study on the circadian rhythm system regulated by intracellular carbon monoxide
Recipient (Institution) Kitagishi Hiroaki(Faculty of Science and Engineering, Doshisha University)
Journal article / other material Chem.Asia J. 2019.14.3320-3328
doi.org/10.1002/asia.201900983
Title of the paper Supramolecular Complexation in Biological Media: NMR Study on Inclusion of an Anionic Tetraarylporphyrin into a Per‐O ‐Methylated β‐Cyclodextrin Cavity in Serum, Blood, and Urine
Title of the research project The RNA-based mechanism underlying pathophysiology in the neurological diseases
Recipient (Institution) Iijima Takatoshi(Tokai University Institute of Innovative Science and Technology)
Journal article / other material Neurochemical Research (in revision)
Title of the paper Distinct expression of SLM2 underlies splicing-dependent trans-synaptic signaling of neurexin across GABAergic neuron subtypes
Journal article / other material iScience. 22:318-335. (2019)
doi: 10.1016/j.isci.2019.11.028.
Title of the paper SAM68-Specific Splicing Is Required for Proper Selection of Alternative 3' UTR Isoforms in the Nervous System.
Title of the research project Elucidation of the molecular basis and physiological significance of autophagic degradation of the nuclear pore complex
Recipient (Institution) Nakatogawa Hitoshi(Sch. of Life Sci. and Tech., Tokyo Institute of Technology)
Journal article / other material Journal of Cell Biology (2020) 219, 7, e201910063
doi.org/10.1083/jcb.201910063
Title of the paper TORC1 inactivation stimulates autophagy of nucleoporin and nuclear pore complexes
Title of the research project Identification of glycosyltransferases involved in biosynthesis of pectin in plant cell wall
Recipient (Institution) Ishimizu Takeshi(Dept. of Biotechnol., Col. of Life Sci., Ritsumeikan Univ.)
Journal article / other material Plant Physiology and Biochemistry (2019) 142, 173-178
10.1016/j.plaphy.2019.07.008
Title of the paper Rhamnogalacturonan I galactosyltransferase: Detection of enzyme activity and its hyperactivation
Journal article / other material Frontiers in Plant Science (2020) 11, 997
10.3389/fpls.2020.00997
Title of the paper Diversity of Pectin Rhamnogalacturonan I Rhamnosyltransferases in Glycosyltransferase Family 106
Journal article / other material Journal of the Japanese Society of Applied Glycoscience (2020) 10, 96-102
doi.org/10.5458/bag.10.2_96
Title of the paper Toward the Elucidation of Molecular Mechanism for Biosynthesis of Pectin in Plant Cell Wall
Title of the research project RNA base modification and RNA processing regulate the maintenance and development of germline stem cells
Recipient (Institution) Kai Toshie(Graduate School of Frontier Biosciences, Osaka University)
Journal article / other material PLOS ONE、2020、Vol.15、e0231114
10.137/journal.pone.0231114
Title of the paper Drosophila MARF1 ensures proper oocyte maturation by regulating nanos expression
Title of the research project The role of desmoplakin in the antidepressant-like effects in the hippocampus
Recipient (Institution) SegiNishida Eri(Segi lab, Dept. of Biol. Sci. and Tech., Tokyo University of Sci)
Journal article / other material Pharmacol Biochem Behav. 186:172767. 2019.
10.1016/j.pbb.2019.172767
Title of the paper Search for factors contributing to resistance to the electroconvulsive seizure treatment model using adrenocorticotrophic hormone-treated mice.
Journal article / other material Neuropsychopharmacol Rep. 41:56-64.2021
10.1002/npr2.12156
Title of the paper Electroconvulsive seizures lead to lipolytic-induced gene expression changes in mediobasal hypothalamus and decreased white adipose tissue mass.
Title of the research project Identification and molecular mechanism of novel calcium transport disease ;possible therapeutic target for bone mineralization defects
Recipient (Institution) Suzuki Yoshiro(Div. Cell Signaling, Nat. Inst. Physiol. Sci.)
Journal article / other material J Physiol Sci (2020) 70(1) 33 - 33
10.1186/s12576-020-00761-2
Title of the paper Novel TRPV6 mutations in the spectrum of transient neonatal hyperparathyroidism
Title of the research project Projection-specific circuit formation in the developing cerebral cortex
Recipient (Institution) Tagawa Yoshiaki(Dept. Physiology, Faculty of Medicine, Kagoshima University)
Journal article / other material Cerebral Cortex, 2021, 31, 1307-1315
doi:10.1093/cercor/bhaa297
Title of the paper Long-range interhemispheric projecion neurons show biased
Title of the research project Peptide foldamers in drug discovery
Recipient (Institution) Demizu Yosuke(Division of Organic Chemistry, NIHS)
Journal article / other material ChemMedChem,14,22(2019)
doi.org/10.1002/cmdc.201900460
Title of the paper Development of Amphipathic Antimicrobial Peptide Foldamers Based on Magainin 2 Sequence
Journal article / other material MedChemComm,10,6,831-1044(2019)
doi.org/10.1039/c9md00166b
Title of the paper Rational design of novel amphipathic antimicrobial peptides focused on the distribution of cationic amino acid residues
Title of the research project Research on metabolic reprogramming induced by cancer development and inflammation
Recipient (Institution) Taniguchi Koji(Department of Microbiology and Immunology, Keio University)
Journal article / other material Mol Cancer Res 2020 18(12):1876-1888.
doi: 10.1158/1541-7786.MCR-20-0186
Title of the paper Autocrine Leukemia Inhibitory Factor Promotes Esophageal Squamous Cell Carcinoma Progression via Src Family Kinase-Dependent Yes-Associated Protein Activation
FY2017 Grant Recipients
Title of the research project Epigenetic and Metabolic Changes on transdifferentiation of white adipocytes
Recipient (Institution) Takeshi Inagaki(Institute for Molecular and Cellular Regulation, Gunma University, professor)
Journal article / other material Endocrine Journal vol.66,No2(February 2019)
Published by The Japan Endocrine Society
Title of the paper Epigenetic regulation of beige adipocyte fate by histone methylation
Journal article / other material Diabetology International(2018) 9:215-223
Title of the paper Histone demethylases regulate adipocyte thermogenesis
Title of the research project Neural circuits that regulate glucose metabolism between hypothalamus and peripheral organs
Recipient (Institution) Kunio Kondoh(National Institute for Physiological Sciences, Assistant Professor )
Journal article / other material Neuroscience Bulletin,20 September 2018
doi:/10.1007/s12264-019-00374-9
Title of the paper Trans-synaptic Neural Circuit-Tracing with Neurotropic Viruses
Title of the research project Heart Cell Molecular Atlas Project to dissect the regulatory mechanisms of circulatory homeostasis
Recipient (Institution) Seitaro Nomura(The University of Tokyo Hospital, Assistant Professor)
Journal article / other material Nature Communications volume 9, Article number: 4435 (2018)
Title of the paper Cardiomyocyte gene programs encoding morphological and functional signatures in cardiac hypertrophy and failure
Journal article / other material Journal of Molecular and Cellular Cardiology,
March 2019Volume 128, Pages 77-89
Title of the paper High-throughput single-molecule RNA imaging analysis reveals heterogeneous responses of cardiomyocytes to hemodynamic overload
Title of the research project Study on the enantioselective total synthesis of dragmacidin E: a natural product with high potential for medicinal chemistry researches
Recipient (Institution) Tetsuhiro Nemoto(Graduate School of Pharmaceutical Sciences, Chiba University, Professor)
Journal article / other material ASIAN JOURNAL OF ORGANIC CHEMISTRY Vol.7,2018,P1730-1742
Title of the paper Synthetic Methods for 3,4‐Fused Tricyclic Indoles via Indole Ring Formation
Title of the research project Development of combination therapy targeting on tumor endothelial cells
Recipient (Institution) Takahisa Murata(The University of Tokyo, Associate Professor)
Journal article / other material THE FASEB JOURNAL,vol33 doi/10.1096/201802153R
Title of the paper Hematopoietic prostaglandin D synthase-derived prostaglandin D2 ameliorates adjuvant-induced joint inflammation in mice
Journal article / other material JCI Insight. 2018;3(23):e120706,doi/10.1172
Title of the paper Inhibition of stromal cell-derived factor-1α/CXCR4 signaling restores the blood-retina barrier in pericyte-deficient mouse retinas
Journal article / other material The journal of pathology ,2019,Vol.248(3),p.280-290
Title of the paper L-PGDS-derived PGD2attenuates acute lung injury by enhancing endothelial barrier formation
Title of the research project Development of super resolution chemical imaging microscopy
Recipient (Institution) Takahashi Yasufumi(Kanazawa University)
Journal article / other material Analytical Chemistry, 2021, 93(13), 5383-5393
doi.org/10.1021/acs.analchem.0c04097
Title of the paper Nanoscale Visualization of Morphological Alteration of Live-Cell Membranes by the Interaction with Oligoarginine Cell-Penetrating Peptides
Journal article / other material Analytical Chemistry, 2020, 92(2), 2159-2167
doi.org/10.1021/acs.analchem.9b04775
Title of the paper High-Speed SICM for the Visualization of Nanoscale Dynamic Structural Changes in Hippocampal Neurons
Title of the research project Exploratory analysis to evaluate mutation spectrum of circulating tumor DNA from metastatic breast cancer treated with aromatase inhibitors
Recipient (Institution) SiewKee Low(Japanese Foundation for Cancer Research)
Journal article / other material Breast Cancer Res Treat. 2020 Apr;180(2):331-341.
10.1007/s10549-019-05512-5
Title of the paper Clinical significance of gene mutation in ctDNA analysis for hormone receptor-positive metastatic breast cancer
Title of the research project Direct reprogramming into cardiac pacemaker cells for a novel regenerative medicine for arrhythmias
Recipient (Institution) Nakao Shu(Ritsumeikan University)
Journal article / other material Biotechnol J 2019;2019:e1900052
10.1002/biot.201900052
Title of the paper Chimeric G-CSF receptor-mediated STAT3 activation contributes to efficient induction of cardiomyocytes from mouse induced pluripotent stem cells.
Title of the research project Molecular mechanism of store-operated Ca2+ entry signalosome and its physiological significance
Recipient (Institution) Baba Yoshihiro(Medical Institute of Bioregulation, Kyushu University)
Journal article / other material The Journal of Biochemistry, mvab063, in press
10.1093/jb/mvab063
Title of the paper ER membrane protein complex 1 interacts with STIM1 and regulates store-operated Ca2+ entry
Title of the research project Decoding the epigenome program which defines normal and tumor endothelial cells
Recipient (Institution) Suzuki Hiromu(Sapporo Medical University)
Journal article / other material Cancer Science, 2020, 111(5):1631-1644
10.1111/cas.14360.
Title of the paper Upregulation of adipocyte enhancer-binding protein 1 in endothelial cells promotes tumor angiogenesis in colorectal cancer.
Title of the research project Elucidation of long non-coding RNA family induced by molecular targeting anti-cancer drugs
Recipient (Institution) Kondo Shigetada(Osaka Prefecture University)
Journal article / other material Neuroscience Bulletin 2019年 33巻 909-920頁
10.1007/s12264-019-00374-9
Title of the paper Trans-synaptic Neural Circuit-Tracing with Neurotropic Viruses
Title of the research project Development of anti-metastatic therapy based on the regulation of vascular integrity
Recipient (Institution) Shindo Takayuki(Shinshu University Graduate School of Medicine)
Journal article / other material Peptides. 110 10-18. 2018
10.1016/j.peptides.2018.10.006
Title of the paper RAMP3 deficiency enhances postmenopausal obesity and metabolic disorders
Journal article / other material Am J Pathol. 189(2):449-466. 2019
10.1016/j.ajpath.2018.10.021
Title of the paper Development of a novel model of central retinal vascular occlusion and the therapeutic potential of the adrenomedullin-RAMP2 system
Journal article / other material Am J Pathol. 191(4):652-668, 2021
10.1016/j.ajpath.2020.12.012
Title of the paper Adrenomedullin-RAMP2 system ameliorates subretinal fibrosis by suppressing epithelial-mesenchymal transition in age-related macular degeneration
Title of the research project Mechanisms underlying commitment to thymic epithelial cells preventing onset of autoimmune diseases
Recipient (Institution) Akiyama Taishin(RIKEN Center for Integrative Medical Science, Team leader)
Journal article / other material Sci Rep. 2019 Dec 27;9(1):19866.
10.1038/s41598-019-56432-9.
Title of the paper Impact of spaceflight on the murine thymus and mitigation by exposure to artificial gravity during spaceflight
Journal article / other material Sci Rep. 2019 May 21;9(1):7654
10.1038/s41598-019-44067-9
Title of the paper Down-regulation of GATA1-dependent erythrocyte-related genes in the spleens of mice exposed to a space travel
Title of the research project Regulation of cellular functions by the nuclelous as a stress sensor
Recipient (Institution) Kimura Keiji(University of Tsukuba)
Journal article / other material Nucleic Acids Research、2020、48、12、6583-6596
10.1093/nar/gkaa449.
Title of the paper Identification of a novel nucleolar protein complex required for mitotic chromosome segregation through centromeric accumulation of Aurora B
Title of the research project Tras-omics approach to elucidate cellular signaling pathways in vascular development, morphogenesis and disease
Recipient (Institution) Nakagawa Osamu(National Cerebral and Cardiovascular Center Research Institute)
Journal article / other material genesis. 59(4): e23416, 2021.
10.1002/dvg.23416
Title of the paper Tmem100-BAC-EGFP mice to selectively mark and purify embryonic endothelial cells of large caliber arteries in mid-gestational vascular formation.
Journal article / other material Dev. Growth Differ. 63(1): 82-92, 2021.
10.1111/dgd.12707
Title of the paper A role of Hey2 transcription factor for right ventricle development through regulation of Tbx2-Mycn pathway during cardiac morphogenesis
Journal article / other material J. Biol. Chem. 295(51):17632-17645, 2020.
10.1074/jbc.RA120.015003
Title of the paper Importance of endothelial Hey1 expression for thoracic great vessel development and its distal enhancer for Notch-dependent endothelial transcription.
Title of the research project Studies on formation and function of extracellular DNA fibers
Recipient (Institution) Saitoh Hisato(Kumamoto University)
Journal article / other material Sci Rep 9, 8451 (2019).
doi.org/10.1038/s41598-019-44817-9
Title of the paper Nanosecond pulsed electric fields induce extracellular release of chromosomal DNA and histone citrullination in neutrophil-differentiated HL-60 cells.
Journal article / other material CellBio, 2020, 9, 14-28.
doi: 10.4236/cellbio.2020.91002.
Title of the paper Three Types of Nuclear Envelope Assemblies Associated with Micronuclei.
Journal article / other material Bioscience, Biotechnology, and Biochemistry, Volume 84, Issue 8, 2 August 2020, Pages 1685-1688,
doi.org/10.1080/09168451.2020.1756737
Title of the paper A fluorescence method to visualize the nuclear boundary by the lipophilic dye DiI
Title of the research project 5-HT2A receptor agonists in treatment to psychiatric disorders
Recipient (Institution) Ibi Daisuke(Meijo University)
Journal article / other material Neurotoxicology and Teratology、2019、76、106837
10.1016/j.ntt.2019.106837
Title of the paper Paternal valproic acid exposure in mice triggers behavioral alterations in offspring
Title of the research project A novel oxytocin neuronal system for regulating lactating behavior in mice
Recipient (Institution) Muroi Yoshikage(Obihiro University of Agriculture and Veterinary Medicine)
Journal article / other material Hormones and Behavior, 2020, 124, 104773
10.1016/j.yhbeh.2020.104773
Title of the paper Oxytocin in the dorsal raphe nucleus antagonizes the inhibition of maternal care induced by food deprivation
Journal article / other material Behavioral Neuroscience, in press
Title of the paper Regulation of maternal care by corticotropin-releasing factor receptors in the dorsal raphe nucleus in mice.
Title of the research project Molecular mechanism for the bifurcation of thymic epithelial cells
Recipient (Institution) Ohigashi Izumi(Institute of Advanced Medical Science, University of Tokushima )
Journal article / other material Cell Reports (2019) 29:2901-2916
doi: 10.1016/j.celrep.2019.10.079
Title of the paper Trans-omics impact of thymoproteasome in cortical thymic epithelial cells
Journal article / other material Journal of Biological Chemistry (2020) 295:1658-1672
doi: 10.1074/jbc.RA119.011144
Title of the paper PITHD1 is a proteasome-interacting protein essential for male fertilization
Journal article / other material Blood advances (2021) 5:99-112
doi: 10.1182/bloodadvances.2020003192
Title of the paper Medullary stromal cells synergize their production and capture of CCL21 for T-cell emigration from neonatal mouse thymus
Title of the research project Novel treatment strategy targeting CCR1-positive myeloid cells in colorectal cancer
Recipient (Institution) Kawada Kenji(Kyoto University)
Journal article / other material Clin Cancer Res. 2019;25(9):2887-2899.
10.1158/1078-0432.CCR-18-3684.
Title of the paper Loss of SMAD4 promotes colorectal cancer progression by recruiting tumor-associated neutrophils via CXCL1/8-CXCR2 axis
Title of the research project Design principle for specific chemical probes toward 3D neuropathology
Recipient (Institution) Tainaka Kazuki(Brain Research Institute, Niigata University)
Journal article / other material Cell Reports, 2018, 24(8), 2196-2210.e9.
10.1016/j.celrep.2018.07.056.
Title of the paper Chemical Landscape for Tissue Clearing Based on Hydrophilic Reagents
FY2016 Grant Recipients
Title of the research project Identification of novel neural processing mechanism by using single transcriptome analysis
Recipient (Institution) Akane Ohta(Konan University, Researcher)
Journal article / other material Cryobiology and Cryotechnology 64.2_53 (2019)
doi./10.20585/
Title of the paper Molecular and Cellular Network Systems Underlying Cold Tolerance of Caenorhabditis elegans
Title of the research project Genome-wide analysis of transcriptional and translational regulation by RNA binding protein PSF in prostate cancer
Recipient (Institution) Kenichi Takayama Department of Functional Biogerontology, Tokyo Metropolitan Inst, Researcher)
Journal article / other material Oncogene 37, 2165-2180, (2018)
https://doi.org/10.1038/s41388-017-0095-x
Title of the paper TRIM25 enhances cell growth and cell survival by modulating p53 signals via interaction with G3BP2 in prostate cancer
Title of the research project Study on the Mechanism of Sex Determination in Germline Stem Cells
Recipient (Institution) Minoru Tanaka(Nagoya University, Professor)
Journal article / other material PLOS Genetics 14, (2018)
https://doi.org/10.1371/journal.pgen.1007259
Title of the paper Germ cells in the teleost fish medaka have an inherent feminizing effect
Title of the research project Elucidation of the onset mechanism of myeloproliferative neoplasm through the erythropoietin receptor
Recipient (Institution) Megumi Tago(Keio University, Associate Professor)
Journal article / other material European Journal of Pharmacology 825, 1-9, (2018)
https://doi.org/10.1016/j.ejphar.2018.02.012
Title of the paper A major component of vitamin E, α-tocopherol inhibits the anti-tumor activity of crizotinib against cells transformed by EML4-ALK
Title of the research project Selective information routing in hippocampal network
Recipient (Institution) Mizuseki Kenji(Osaka City University Graduate School of Medicine, Professor)
Journal article / other material Neuroscience Research 118, 30-47, (2017)
http://dx.doi.org/10.1016/j-neures.2017.04.018
Title of the paper Hippocampal information proccessing across sleep/wake cycles
FY2015 Grant Recipients
Title of the research project Control of host immune responses through innate pattern-recognition receptors that recognize Mycobacterium tuberculosis virulence lipids
Recipient (Institution) Hiromitsu Hara, Kagoshima University Graduate School of Medical and Dental Sciences, Professor
Journal article / other material Nature Communications 6:5555
doi:10.1038/ncomms6555
Title of the paper Clustering of CARMA1 through SH3-GUK domain interactions is required for its activation of NF-κB signaling
Title of the research project Molecular mechanism of plant cell growth via NIMA-related kinases
Recipient (Institution) Hiroyasu Motose, Okayama University, Department of Biological Science, Graduate School of Natural Science & Technology, Associate Professor
Journal article / other material Development (2018) 145, dev154617
doi:10.1242/dev.154617
Title of the paper An evolutionarily conserved NIMA-related kinase directs rhizoid tip growth in the basal land plant Merchantia polymorpha
Journal article / other material Scientific Report 7, 7826
doi:10.1038/s41598-017-08453-5
Title of the paper Directional cell expansion requires NIMA-related kinase 6 (NEK6)-mediated cortical microtubule destabilization
Title of the research project Analysis of a signal through ER required for the induction of axon regeneration
Recipient (Institution) Naoki Hisamoto, Nagoya university Graduate school of Science, Associate Professor
Journal article / other material PLoS 12(12):e1006475
doi:10.1371/journal.pgen.1006475
Title of the paper The C. elegans Discoidin Domain Receptor DDR-2 Modulates the Met-like RTK-JNK Singnaling Pathway in Axon Regeneration
Title of the research project Development of molecular delivery system using cell membrane penetrating DNA nanostructures
Recipient (Institution) Masayuki Endo, Kyoto University, Institute for Integrated Cell-Material Sciences (WPI-iCeMS),
Journal article / other material Chem. Eur. J 23, 3979-3985 (2017)
doi:10.1002/chem.201605616
Title of the paper A photoregulated DNA-Based Rotary System and Direct Observation of Its Rotational Movement
Title of the research project Functional significance of Chandelier cell in cortical microcircuit
Recipient (Institution) Yoshiyuki Kubota, National Institute for Physiological Sciences, Associate professor
Journal article / other material Front Neural Circuits 10, 27 (2016)
doi:10.3389/fncir.2016.00027
Title of the paper The Diversity of Cortical Inhibitory Synapses
Journal article / other material Nat Commun 9, 437 (2018)
doi:10.1038/s41467-017-02768-7
Title of the paper A catructurerbon nanotube tape for serial-section electron microscopy of brain ultra
Title of the research project Cortical synaptic plasticity for coexistence of chronic pain and anxiety neurosis
Recipient (Institution) Kohei Koga, Hirosaki University Department of Neurophysiology, Assistant
Journal article / other material J. Neurochem. 141 486-498 (2017)
Title of the paper Neuronal and microglial mechanisms for neuropathic pain in the spinal dorsal horn and anterior cingulate cortex
Title of the research project Functional analysis of a novel silencing mechanism in higher plants
Recipient (Institution) Kei-ichiro Mishiba, Graduate School of Life and Environmental Science, Osaka Prefecture University, Associate
Journal article / other material Science Direct 1860, 861-869 (2017)
https:doi.org/10.1016/j.bbagrm.2017.06.001
Title of the paper Biochimica et Biophysica Acta (BBA) Gene Regulatory Mechanisms
Title of the research project The origin of animal multicellular system an approach from genome editing of unicellular holozoans
Recipient (Institution) Hiroshi Suga, Prefectural University of Hiroshima, Faculty of Life and Environmental Sciences, Associate Professor
Journal article / other material eLife 2017 6:e26036
doi:10.7554/eLife.26036
Title of the paper Dynamics of genomic innovation in the unicellular ancestry of animals
Title of the research project Regulating microtubule arrays for neuronal dendrite growth and for neuronal regeneration
Recipient (Institution) Adrian Moore(RIKEN Center for Brain Science)
Journal article / other material Plant Physiology,182,1979-1990(2020)
Title of the paper Atypical Myosin Tunes Dendrite Arbor Subdivision
FY2014 Grant Recipients
Title of the research project Effect of dendritic cell based vaccine against highly virulent cryptococcal infection
Recipient (Institution) Yuki Kinjo (National Institute of Infectious Diseases, Department of Chemotherapy and Mycoses, LaboratoryHead)
Journal article / other material Frontiers in Cellular and infection Microbiology 5:101 Doi: 10.3389/fcimb.2015.00101 (2016)
Title of the paper Evasion of innate immune responses by the highly virulent Cryptococcus gatti by altering capsule glucuronoxylomannan structure
Journal article / other material J Infect Chemother., 21, 831-6 (2015)
Title of the paper Interferon-γ promotes phagocytosis of Cryptococcus neoformans but not Cryptococcus gatti by murine macrophages
Journal article / other material Vaccine Design: methods and Protocols: volume 1: vaccines for Human Diseases, method in Molecular Biology, vol 1.1403, DOI 10.1007/978-1-49393387-7_30
Title of the paper Dendric cell-based vaccine against fungal infection
Title of the research project Nano scale analysis of lipid molecules of biomembrane topology
Recipient (Institution) Akikazu Fujita (Kagoshima University, Joint Faculty of Veterinary Medicine, Professor)
Journal article / other material Biochimica Biophysica Acta, 1858, 1298-305 (2016)
Title of the paper Nanoscale analysis reveals agonist-sensitive and heterogeneous pools of phosphatidylinositol 4-phosphate in the plasma membrane
Title of the research project Positive feed-forward loop of mTOR complex links cellular metabolism to targeted therapy resistance
Recipient (Institution) Kenta Masui (Laboratory of Neuropathology, Tokyo Metropolitan Institute of Medical Science, Chief Researcher)
Journal article / other material Brain pathology, 25, 755-9 (2015)
Title of the paper mTORC2 and metabolic reprogramming in GBM: at the interface of genetics and environment
Journal article / other material www.pnas.org/cgi/doi/10.1073/pnas.1511759112
Title of the paper Glucose-dependent acetylation of rictor promotes targeted cancer therapy resistance
Title of the research project Analysis of molecular mechanisms for cell fate determination of retinal interneurons
Recipient (Institution) Rikako Sanuki (Osaka University, Institute for Protein Research, Assistant Professor)
Journal article / other material J Neuroscience, 35, 8004-20 (2015)
Title of the paper Prdm13 regulates subtype specification of retinal amacrine interneurons and modulates visual sensitivity
Journal article / other material Molecular and Cellular Biology, 35, 2583-96 (2015)
Title of the paper Rax homoprotein regulates photoreceptor cell maturation and survival in association with Crx in the postnatal mouse retina
Title of the research project Drug discovery for neuropathic pain from processed aconite root
Recipient (Institution) Toshiaki Makino (Nagoya City University,Graduate School of Pharmaceutical Sciences, Professor)
Journal article / other material Journal of Ethnopharmacoloy, 186, 44-52 (2016)
Title of the paper Processed aconite root and its active ingredient neoline may alleviate oxaliplatin-induced peripheral neuropathic pain
Title of the research project Development of a comprehensive synthetic strategy and study of biological activity of yuzurimine alkaloids
Recipient (Institution) Ichiro Hayakawa (Graduate School of Natural Science and Technology, Okayama University, Associate Professor)
Journal article / other material Chem. Commun., 51, 11568-71 (2015)
Title of the paper Construction of the [6-7-5-5] tetracyclic core of all the carbocyclic frameworks of yuzurimine-type alkaloids
Journal article / other material Org. Biomol. Chem., 13, 9969-76 (2015)
Title of the paper Synthesis and structure-activity relationships for cytotoxicity and apoptosis-inducing activity of (+)-halichonine B
Title of the research project Development of novel therapy for peripheral artery disease using ApoA-I mimetic peptide
Recipient (Institution) Satoshi Imaizumi (Fukuoka University School of Medicine, Assistant Professor)
Journal article / other material International Journal of Cardiology, 207, 317-25 (2016)
Title of the paper The ApoA-I mimetic peptide FAMP promotes recovery from hindlimb ischemia through a nitric oxide (NO)-related pathway
Title of the research project Regulation mechanisms of retroelements by RNA virus
Recipient (Institution) Tomoyuki Honda (Institute for Virus Research, Kyoto University, Assistant Professor)
Journal article / other material Cell reports, 12, 1948-54 (2015)
Title of the paper Transcription profiling demonstrates epigenetic control of non-retroviral RNA virus-derived elements in the human genome
Journal article / other material Frontiers in Chemostry, 4, doi:10.3389/fchem.2016.00021
Title of the paper Links between human LINE-1 retrotransposons and hepatitis virus-related hepatocellular carcinoma
Journal article / other material Mobile Genetic Elements, 6, Doi: 10.1080/2159256X.2016. 1165785
Title of the paper Endogenous non-retroviral RNA virus elements evidence a novel type of antiviral immunity
Journal article / other material Nature Scientific reports, 6, 26154, Doi: 10.1038/srep26154
Title of the paper Long-term expression of miRNA for RNA interface using a novel vector system based on a negative-strand RNA virus
Title of the research project Research on the regulation of chronic inflammatory disease by plasmacytoid dendritic cells
Recipient (Institution) Hideaki Takagi (Faculty of Medicine, University of Miyazaki, Assistant Professor)
Journal article / other material Nature Communications, 7, 11273,Doi:10.1038/nocommons11273
Title of the paper Plasmacytoid dendritic cells orchestrate TLR7-mediated innate and adaptive immunity for the initiation of autoimmune inflammation
Title of the research project Genome-wide screening of endocytosis of GPCR
Recipient (Institution) Junko Toshima (Faculty of Science And Engineering, Waseda University, Associate Professor)
Journal article / other material Biochemical and Biophysical Research Communications, xxx, 1-7 (2016).doi.org/10.1016/j.bbrc.2016.05.099
Title of the paper Lipid droplet proteins, Lds1p, Lds2p and Rrt8p, are implicated in membrane protein transport associated with ergosterol
Journal article / other material Journal of Cell Science, 129, 367-79 (2016), doi:10.1242/jcs.176651
Title of the paper Srv2/CAP is required for polarized actin cable assembly and patch internalization during clathrin-mediated endocytosis
FY2013 Grant Recipients
Title of the research project CARTS-mediated protein transport from the Golgi complex to the cell surface
Recipient (Institution) Yuichi Wakana(Tokyo University of Pharmacy and Life Sciences, School of Life Sciences)
Journal article / other material Molecular Biology of the Cell, 26, 4686-4699, (2015)
Title of the paper CARTS biogenesis requires VAP-lipid transfer protein complexes functioning at the endoplasmic reticulum-Golgi interface
Title of the research project Discovery of New Drug Candidates Based on Development of Site-selective Direct Functionalization of Pyridones
Recipient (Institution) Koji Hirano(Department of Applied Chemistry, Graduate School of Engineering, Osaka University)
Journal article / other material Angewandte Communications: 53, 10784-10788 (2014)
Title of the paper Copper-Mediated C6-Selective Dehydrogenative Heteroarylation of 2-Pyridones with 1,3-Azoles
Title of the research project Research on Asymmetric Membrane Elongation Critical for Symmetric Cell Division
Recipient (Institution) Tomomi Kiyomitsu (Nagoya University, Graduate School of Science, Assistant Professor)
Journal article / other material Trends in Cell Biology, May Vol.25, No.5 286-295 (2015)
Title of the paper Mechanisms of daughter cell-size control during cell division
Title of the research project ”Memory priming” that determines the start of the critical period for learning
Recipient (Institution) Koichi Homma (Teikyo University, Faculty of Pharmaceutical Sciences, Professor)
Journal article / other material Communicative & Integrative Biology: Volume7 Issue5 1-4 October 1 , (2014)
Title of the paper Expression of the voltage-sensing phosphatase gene in the chick embryonic tissues and in the adult cerebellum
Title of the research project Dissecting the mechanism of cellular senescence that regulates tumor microenvironment
Recipient (Institution) Shizue Ohsawa (Kyoto University, Graduate School of Biostudies, Associate Professor)
Journal article / other material Developmental Biology 395, 19-28(2014)
Title of the paper Loss of Rab5 drives non-autonomous cell proliferation through TNF and Ras signaling in Drosophila
Journal article / other material Nature Communications DOI:10.1038/ncomms6264 (2014)
Title of the paper Mitochondrial defects trigger proliferation of neighbouring cells via a senescence-associated secretory phenotype in Drosophila
Title of the research project Development of novel treatment strategies targeting the R-spondin-LGR5 axis of brain tumor stem cells
Recipient (Institution) Ryo Nasu (Kyoto Prefectural University of Medicine, Assistant Professor)
Journal article / other material BBRC(Biochemical and Biophysical Research Communications), 459, 411-415(2015)
Title of the paper Thr160 of Axin1 is critical for the formation and function of the β-catenin destruction complex
Title of the research project Elucidating how the auditory information is integrated by morphological techniques
Recipient (Institution) Tetsufumi Ito (University of Fukui, Faculty of Medical Sciences, Assistant Professor)
Journal article / other material The Journal of Comparative Neurology 00:00-00, (2015)
Title of the paper Convergence of Lemniscal and Local Excitatory Inputs on Large GABAergic Tectothalamic Neurons
Journal article / other material Brain Research doi.org/10.1016 (2014)
Title of the paper Determining auditory-evoked activities from multiple cells in layer 1 of the dorsal cortex of the inferior colliculus of mice by in vivo calcium imaging
Title of the research project Membrane type-1 matrix metalloproteinase in multiple myeloma: a novel modulator of the microenvironment
Recipient (Institution) Beate Heissig (The University of Tokyo, The Institute of Medical Science, Associate Professor)
Journal article / other material Leukemia 29,145-156 (2015)
Title of the paper Inhibition of plasmin attenuates murine acute graft-versus-host disease mortality by suppressing the matrix metalloproteinase-9-dependent inflammatory cytokine storm and effector cell trafficking
Title of the research project Research on the role of the novel adipocytokine in heart disease
Recipient (Institution) Noriyuki Ouchi (Nagoya University, Graduate School of Medicine, Professor)
Journal article / other material The FASEB Journal Vol.29 January 141-151 (2015)
Title of the paper Adipose-derived protein omentin prevents neointimal formation after arterial injury
Journal article / other material Circ Heart Fail DOI:10.1161/114.001647(2015)
Title of the paper Neuron-Derived Neurotrophic Factor Ameliorates Adverse Cardiac Remodeling After Experimental Myocardial Infarction
Title of the research project The apoptosis-inducing mechanism of biselyngbyaside, a marine macrolide
Recipient (Institution) Kiyotake Suenaga (Keio University, Faculty of Science and Technology, Associate Professor)
Journal article / other material Organic Letters, 17, 652-655 (2015)
Title of the paper Jahanyne, an Apoptosis-Inducing Lipopeptide from the Marine Cyanobacterium Lyngbya sp.
Journal article / other material Journal of Natural Products78, 901-908 (2015)
Title of the paper Mebamamides A and B, Cyclic Lipopeptides Isolated from the Green Alga Derbesia marina
Title of the research project Functional analysis of a novel suppressive factor at fertilization
Recipient (Institution) Naofumi Miwa (Toho University, School of Medicine, Associate Professor)
Journal article / other material Molecules 20, 9468-9486 (2015)
Title of the paper Protein-Carbohydrate Interaction between Sperm and the Egg-Coating Envelope and Its Regulation by Dicalcin, a Xenopus laevis Zona Pellucida Protein-Associated Protein
Title of the research project Elucidation of the novel signal network that regulates trafficking of secretory lysosomes
Recipient (Institution) Yoshinori Fukui (Kyushu University, Medical Institute of Bioregulation, Professor)
Journal article / other material The Journal of Experimental Medici: Vol.211 No.7 1407-14019 (2014)
Title of the paper DOCK5 functions as a key signaling adaptor that links FcƐRI signals to microtubule dynamics during mast cell degranulation
Title of the research project The Identification of Exosomal Micro RNA Specific for the Recurrence of Hepatocellular Carcinoma
Recipient (Institution) Keishi Sugimachi (Kyushu University Beppu Hospital, Associate Professor)
Journal article / other material British Journal of Cancer: doi: 10.1038/bjc 2014.621 (2014)
Title of the paper Identification of a bona fide microRNA biomarker in serum exosomes that predicts hepatocellular carcinoma recurrence after liver transplantation
Title of the research project Development of a novel catalytic asymmetric method for the incorporation of a biologically significant trifluoromethyl group
Recipient (Institution) Yoshitaka Hamashima (University of Shizuoka, School of Pharmaceutical Sciences, Professor)
Journal article / other material Chemistry European Journal doi:10.1002/chem.201403447 20, 12061-12065 (2014)
Title of the paper Dual Catalysis wit Copper and Rhenium for Trifluoromethylation of Propargylic Alcohols: Efficient Synthesis of α-Trifluoromethylated Enones
Title of the research project Spatiotemporal analysis of oncogenic signaling by Kit tyrosine kinase ~Mechanism of autonomous proliferation in mastocytosis and gastrointestinal stromal tumor (GIST)~
Recipient (Institution) Yuuki Obata (Tokyo University of Science, Research Institute for Biomedical Sciences, Assistant Professor)
Journal article / other material Nature Communications Doi: 10.1038/ncomms6715
Title of the paper Oncogenic Kit signals on endolysosomes and endoplasmic reticulum are essential for neoplastic mast cell proliferation
FY2012 Grant Recipients
Title of the research project Molecular mechanism of temperature response through secretory signaling
Recipient (Institution) Atsushi Kuhara (Faculty of Science and Engineering, Konan University)
Journal article / other material Neurosci Res, 76, 119-24 (2013)
Title of the paper Molecular mechanism for trimetric G protein-coupled thermosensation and synaptic regulation in the temperature repsonse circuit of Caenorhabditis elegans
Title of the research project Elucidation of the mechanisms by which impaired clearance of apoptotic cells results in severe inflammation
Recipient (Institution) Hiroyasu Nakano (Graduate School of Medicine, Juntendo University)
Journal article / other material Biochem Biophys Res Commun, 436, 212-6 (2013)
Title of the paper Critical contribution of oxidative stress to TNF α-induced necrosis downstream of RIPK1 activation
Title of the research project Comprehensive proteomicanalysis of molecules that are targeted for cancer prognosis or therapy
Recipient (Institution) Kiyotsugu Yoshida (School of Medicine, Jikei University)
Journal article / other material Proc Natl Acad Sci USA , 111, 717-22 (2014)
Title of the paper Induction of amphyregulin by p53 promotes apoptosis via control of microRNA biogenesis in response to DNA damage
Journal article / other material Cancer Lett, 339, 214-25 (2013)
Title of the paper DYRK2 controls the epithelial-mesenchymal transition in breast cancer by degrading Snail
Title of the research project Explorative study on lysine demethylase inhibitors by rational drug design
Recipient (Institution) Takayoshi Suzuki (Department of Chemistry, Kyoto Prefectural University of Medicine)
Journal article / other material J Med Chem, 56, 7222-31 (2013)
Title of the paper Identification of the KDM2/7 histone lysine demethylase subfamily inhibitor and its antiproliferative activity
Journal article / other material Angew Chem Int Ed Engl, 52, 8620-4 (2013)
Title of the paper Lysine-specific demethylase 1-selective inactivators: protein-targeted drug delivery mechanism
Journal article / other material Comput Struct Biotechnol J, 9, e201402002 (2014)
Title of the paper Synthesis, LSD1 inhibitory activity, and LSD1 binding model of optically pure lysine-PCPA conjugates
Title of the research project Synthesis of anticancer anthracycline antibiotics having aza-spiro structure
Recipient (Institution) Mitsuru Kitamura (Graduate School of Engineering, Kyushu Institute of Technology)
Journal article / other material Tetrahedron Lett, 55, 1653-6 (2014)
Title of the paper Synthetic study of kosinostatin aglycone: synthesis of BCDE rings using alkoxycarbonylmethylation of diazonaphtoquinone
Title of the research project Identification of cytidine deaminase activity for elucidating the molecular mechanism of plant organelle RNA editing
Recipient (Institution) Mamoru Sugita (Center for Gene Research, Nagoya University)
Journal article / other material Plant Cell Physiol, 54, 1907-16 (2013)
Title of the paper Two DYW subclass PPR proteins are involved in RNA editing of ccmFc and atp9 transcripts in the Moss Physcomitrella patens: first completes set of PPR editing factors in plant mitochondria
Title of the research project RAC1 inhibitor is an anti-tumor metastasis drug
Recipient (Institution) Satoru Yokoyama (Institute of Natural Medicine, Toyama University)
Journal article / other material Cancer Sci, 105, 788-94 (2014)
Title of the paper RAC1 inhibition as a therapeutic target for gefitinib-resistant non-small-cell lung cancer
Title of the research project Molecular mechanism of Derlin family-mediated novel endoplasmic reticulum quality control system
Recipient (Institution) Hideki Nishitoh (Department of Medical Sciences, University of Miyazaki)
Journal article / other material Genes(Basel), 4, 306-33 (2013)
Title of the paper Signaling pathways from the endoplasmic reticulum and their roles in disease
Title of the research project Epigenetic regulation by nuclear pore complex in cancer progression.
Recipient (Institution) Richard Wong (Institute of Science and Engineering, Kanazawa University)
Journal article / other material Cell Cycle, 10, 1456-67 (2011)
Title of the paper RNA export factor RAE1 contributes to NUP98-HOXA9-mediated leukemogenesis
Title of the research project Elucidation of molecular functions of Imp3 in osteosarcoma progression, and development of novel anti-Imp3 targeted therapeutic approach
Recipient (Institution) Takatsune Shimizu (Faculty of Pharmaceutical Sciences, Hoshi University)
Journal article / other material Cancer Res, 74, 6531-41 (2014)
Title of the paper IGF2 preserves osteosarcoma cell survival by creating an autophagic state of dormancy that protects cells against chemotherapeutic stress
Title of the research project Synthetic Studies on the virulent cell wall lipid of Mycobacterium tuberculosis
Recipient (Institution) Seijiro Hosokawa (Faculty of Science and Engineering, Waseda University)
Journal article / other material Org Lett, 16, 4106-9 (2014)
Title of the paper Stereoselective acylation of the E,E-vinylketene Silyl N,O-acetal and its application to the synthesis of khafrefungin
Title of the research project Development of an orange-colored bimolecular fluorescence complementation (BiFC) assay
Recipient (Institution) Yutaka Kodama (Center for Bioscience Research and Education, Utsunomiya University)
Journal article / other material The 12th Japan Prize in Agrecultural Sciences, Achievement Award for Young Scientists (The Foundation of Agrecultural Sciences of Japan)
Title of the paper Visualization of protein-protein interactions in living cells
Title of the research project Regulation of plasma membrane receptor-like kinase functions by endoplasmic reticulum quality control in plant cells
Recipient (Institution) Shuh-ichi Nishikawa(Faculty of Science, Niigata University)
Journal article / other material Plant Physiology,182,1979-1990(2020)
Title of the paper ERdj3B-Mediated Quality Control Maintains Anther
Development at High Temperatures
FY2011 Grant Recipients
Title of the research project Molecular mechanism of self-renewal and proliferation of a hematopoietic cell due to HMGA2 expression
Recipient (Institution) Kazuhiko Ikeda (Department of Cardiology and Hematology, Fukushima Medical University)
Journal article / other material Clin Lymphoma Myeloma Leuk, 14, e69-72 (2014)
Title of the paper Somatic 15q break after long-term stable disease in acute myeloid leukemia
Journal article / other material Br J Haematol, 168, 388-49 (2015)
Title of the paper Dysregulation of the MIRLET7/HMGA2 axis with methylation of the CDKN2A promoter in myeloproliferative neoplasms
Title of the research project The Role of transcription factor Iκβ-ζ in immunity homeostasis
Recipient (Institution) Takashi Maruyama (Graduate School of Life Sciences, Tohoku University)
Journal article / other material PLoS One, 9, e110838 (2014)
Title of the paper The nuclear IκB family protein IκBNS influences the susceptibility to experimental autoimmune encephalomyelitis in a murine model
FY2007 Grant Recipients
Title of the research project Analysis of new zebrafish mutants that show the defects in gut epithelium formation.
Recipient (Institution) Yutaka Kikuchi (Graduate School of Science, Hiroshima University)
Journal article / other material PLoS One, 7, e33675 (2012)
Title of the paper DEAD-box protein Ddx46 is required for the development of the digestive organs and brain in zebrafish